Archives : Nov-2020

first_imgCroatia was recently awarded another recognition in terms of tourist attractiveness. The largest and most famous tourist guide in the world, Lonely planet, has published a list of leading European destinations that should definitely be visited this summer. Northern Dalmatia, a region that has ‘all the cultural features of the Adriatic and at the same time has a stunningly untouched nature that is almost non-existent elsewhere in Europe’, took a high tenth place.Recognitions like this contribute to the success of the tourist season, and preparations have long since begun by hiring quality tourism workers. If you are looking for a job on the Adriatic, check the job offer on the MojPosao portal. This week we highlight the following open competitions:The Karisma hotel group employs a large number of employees in the positions of waiter, bartender, chef, assistant kitchen manager and pastry chef. In addition to a pleasant and motivating work environment, the employer provides accommodation and food. You can send your application via portal, no later than June 1.Larger number category B driver employed by the Connecto Mare travel agency. We are looking for employees in the area of ​​Split, Pula, Rijeka, Zadar. Šibenik, Makarska and Dubrovnik. The salary is 6.000 kuna net + tips, and the employer also provides education and an official mobile phone and tablet.If you are ready to work abroad, apply to work on cruisers of the Swiss company Viking River Cruises. You can read information about work tasks, salary and conditions in ads for maids, cooks, auxiliary workers and waiters.Gulliver travel invites you to apply for the job of travel agent and tour guide. Accommodation is available for candidates from other counties. You can find everything about the job and the required conditions at MojPosao portal.Dubrovnik restaurants Panorama, Nautika and Dubravka are looking for a larger number of new employees this year as well. All information can be found at ads.The city cafe is also looking for more employees. You can send your application for the desired job position via portal, no later than June 16.Jadranka hotels are looking for chefs, waiters, maids and lifeguards. The employer provides professional education, employment contract with the possibility of long-term employment, accommodation and food.Primosten hotels are looking for chef to prepare a´la carte dishes. The candidate is covered for travel expenses, and accommodation and food are provided at the workplace. Sign up today!Tavern Bepo in the Nin area is also looking for a chef. My registration you can send no later than June 8th.last_img read more

first_imgThe 2017 tourist year for the Kvarner Tourist Board begins with engagement in emitting markets, and the first stop is the German market. By the way, 2016 was a record tourist year in Kvarner, which ended with 5% more arrivals and 6% more overnight stays than in the same period in 2015.The German market for Kvarner is unrivaled market number one, both for Kvarner and for Croatia, and in terms of share in overnight stays, which in 2016 amounted to 31%, ie more than half a million arrivals (524.586) and almost 4 million overnight stays (3.939.711) of German guests, while the second strongest market is Slovenia with a share of 14% in total overnight stays.That the German market is the most important for European destinations is also shown by the CNTB data which state that Germany is the third tourist market in the world after the USA and China and the first in Europe with 69,1 million trips longer than four days and 77 million shorter trips. on which the Germans spend almost 90 billion euros. “The main feature that has marked the German tourism market and that is visible in the past period is stability. The topic of travel and tourism is high on the list of priorities of German citizens, and various segments of social life are being upgraded around these concepts. Tourist topics are very common in the media and the average German is an experienced traveler. ”Is stated in the document Profile of Emitting Markets 2016, which you can view in full here.Photo: TZ KvarnerThe trend of growth in tourist traffic from the German market in Kvarner has continued, and in 2016 there were as many as 8% more Germans, and they realized 9% more overnight stays than in 2015. Data that is a factor more to focus on the German market with the aim of bringing in even more German tourists. Thus, the Kvarner Tourist Board opened its promotional and fair promotion at one of the world’s largest fairs CMT Stuttgart.At CMT, on an area of ​​105.000 m2, more than 2.000 exhibitors from about 90 countries are exhibiting, and the fair is followed daily by about 1.500 accredited journalists from 21 countries. “CMT is a very popular and visited fair, interest in the offer of Kvarner is great, avIn addition to all the above, all participants in the promotion, along with the Kvarner Tourist Board, should achieve significant marketing value with this performance, as well as influence a larger number of guests and overnight stays from Germany and one of the richest German states Baden – Württemberg. We believe that the proximity and accessibility of Kvarner, and a good image of the region with the promotion of attractions for all guests, will contribute to the fact that they choose Kvarner for their vacation in 2017.. “Said the director of the Kvarner Tourist Board, Ph.D. Irena Persic Zivadinov.Since the appearance of Kvarner as a partner region of the CMT fair in 2015, which was a huge marketing and commercial success, and the achieved media value was 2,31 million euros, and this fair has remained the most important point in promoting the camping offer of Kvarner they point out from the Kvarner Tourist Board and add that PR activities have continued throughout the year and relations with the media are especially nurtured, and many German journalists have visited Kvarner and reported on current events from the tourist offer.Photo: TZ KvarnerThe Kvarner Tourist Board, which represents the offer of the entire Kvarner, proposed to the tourist boards and representatives of the economy, primarily camps, to join the joint performance, and thus rationalize funds, increase joint promotion and make the most of promotion opportunities.The following entities responded to the invitation of the Kvarner Tourist Board: the Tourist Board of the Island of Krk – Camps of the Island of Krk, Cresanka dd, Cres, Imperial dd, Rab, the Tourist Board of the City of Crikvenica. ” Only by joint efforts and cooperation with all those who carry the tourist offer of the region do we achieve and show the strength and attractiveness of the region, and ultimately we can achieve better results even than the record 2016. It is extremely important that the performance is realized in cooperation with economic entities from the Kvarner area and tourist boards. That way, the whole performance is more representative and efficient. ” concludes Peršić Živadinov and adds that the most sought-after material is “Kvarner Magazine” (newly printed edition for 2017) with the offer of all Kvarner subregions.last_img read more

first_imgIt is possible to submit an item that is already used as a souvenir and / or a proposal for a completely new souvenir, and with each submitted proposal it is necessary to enclose: original name with a story of origin and origin, explain its origin and connection with the Cres-Lošinj archipelago, date of creation, technique, description of production and description of materials, name of legal or natural person, proof of registration of activity, contact of the author with address, e-mail, website, approximate price of the product on the market, statement that the proposed work is a work of authorship, signed by the author.Proposals with information about the author and the listed attachments should be submitted to the Tourist Office of the Tourist Board of the City of Mali Lošinj until April 15, 2017. See the invitation to submit proposals for original souvenirs of the City of Mali Lošinj here For the eleventh year in a row, with the aim of promoting and encouraging the initiative for quality design of indigenous souvenirs and products, the Tourist Board of the City of Mali Lošinj is selecting original souvenirs of the City of Mali Lošinj; unique, inspired by the landscape of the Cres-Lošinj archipelago.Souvenir proposals that meet the criteria of the original souvenir of the City of Mali Lošinj (artistic and design originality and recognizability of Cres-Lošinj origin, quality of workmanship and achieved recognition, originality, economic accessibility, practicality and possible applicability in everyday use), selected by the evaluation committee Original Lošinj souvenirs in 2017.“The certificate itself is proof that the souvenir, in addition to artistic and design originality and quality workmanship from natural materials, also expresses the recognizability of its origin associated with the Cres-Lošinj archipelago. The souvenir must tell the guest a story about tradition, history and customs, so the author is obliged to tell the story through inspiration, motivation, as well as ways of making and a description of the materials from which the souvenir is made. ” they point out from the Tourist Board of the City of Mali Lošinj and add that the condition for registration is that the souvenir is sold at a minimum of one point of sale (shop or web shop).last_img read more

first_imgShare Pinterest Email A new study suggests that those at risk of hoarding disorder may have serious complaints about sleep.Results show that participants at risk of hoarding disorder scored significantly higher on the Sleep Habits Survey (SH) and on three sub-scales of the Pittsburgh Sleep Quality Index (PSQI), including sleep latency; sleep disturbances and daytime disturbances.“Hoarders typically have problems with decision making and executive function; poor sleep is known to compromise cognition generally, so if hoarders have cluttered/unusable bedrooms (and less comfortable, functional beds), any existing risk for cognitive dysfunction, depression and stress may increase as sleep quality worsens,” said lead author Pamela Thacher, assistant professor of psychology at St. Lawrence University in Canton, N.Y. Share on Twittercenter_img The research abstract was published recently in an online supplement of the journal Sleep and will be presented Monday, June 8, in Seattle, Washington, at SLEEP 2015, the 29th annual meeting of the Associated Professional Sleep Societies LLC.The study group comprised a sample of respondents from Amazon’s Mechanical Turk website. Their advertisement asked for those interested in hoarding, sleep, or clutter, whether or not they had problems with these areas. Questionnaires included: Demographics; PSQI; Clutter and Hoarding Rating Scale (CHRS) and SH.The study was the focus of Thacher’s honor student last year, second author, Alexis Reinheimer, a psychology major at St. Lawrence University in Canton, N.Y. Share on Facebook LinkedInlast_img read more

first_imgLinkedIn “In our study, we used Mooney faces which intentionally violated two expectations: Firstly, that we always see faces oriented upright, and secondly, that light comes from above. The facial recognition performance became noticably poorer and slower as a result”, Prof. Michael Wibral from the Brain Imaging Center at the Goethe University explained.What happens in the brain in this situation? The current theory, the “Predictive Coding” theory, suggests that signals only have to be sent to higher brain areas for processing if predictions aren’t met. Thus an increase in signal activity towards higher brain areas should occur. However, there are also competing theories which predict the exact opposite.Testing the theory directly only became possible recently, when Frankfurt scientists at the Strüngmann Institute discovered that brain wave activity at about 90 Hertz increases when signals are sent from lower to higher brain areas. “If a predictive error is induced by generating images which contradict the everyday visual reality learned over the course of a lifetime, then we should see an increase in brain wave activity at 90 Hertz in response to an error. We were able to confirm this experimentally”, Wibral explained.“And we were also able to show that the intensity of these ‘error brain waves’ increases along with the time necessary for recognition. This shows that these brain waves don’t just initiate a correction, but also play a causal role in our perception”, Wibral continued.The results are important specifically because these brain waves also appear to be significantly impaired in patients with schizophrenia and autism spectrum disorders. This was shown through measurements taken in the laboratory of the Frankfurt Brain Imaging Centre over the past few years. The researchers are now hoping to gain a better understanding of both illnesses and to find ways of helping patients to correct their predictive errors more effectively. Share on Twitter Email Our brain recognizes objects within milliseconds, even if it only receives rudimentary visual information. Researchers believe that reliable and fast recognition works because the brain is constantly making predictions about objects in the field of view and is comparing these with incoming information. Only if mismatches occur in this process do higher areas of the brain have to be notified of the error in order to make active corrections to the predictions.Now scientists at the Goethe University have confirmed this hypothesis. As they report in the current edition of the Journal of Neuroscience, those brain waves that are sent to higher brain areas increase their activity when a predictive error occurs. These results also promise a better understanding of schizophrenia and autism spectrum disorders.In order to induce predictive errors in their subjects, the researchers showed them so-called Mooney faces, named after their inventor Craig Mooney. These are photographs of faces which have been reduced entirely to black and white. We usually recognize these easily. We can even give details about the gender, age and facial expression – despite the fact that only the borders between black and white contain any information about the face. Moreover, even this minimal amount of information is ambiguous, because the boundaries either represent the transition between light and cast shadows or they confine the object itself.center_img Pinterest Share on Facebook Sharelast_img read more

first_imgEmail LinkedIn Today, more than 5.1 million Americans live with Alzheimer’s disease, a devastating type of dementia that plagues memory and thinking. That number is expected to triple in the coming decades. Moreover, according to a 2012 survey, Americans fear Alzheimer’s more than any other disease.But studies looking into treatments for Alzheimer’s disease have been frustratingly disappointing.“There is no cure for Alzheimer’s disease,” said Liqin Zhao, assistant professor of pharmacology and toxicology at the University of Kansas School of Pharmacy. “Five available Alzheimer’s disease drugs were all approved by FDA 10 years ago, and they provide only temporary symptomatic relief for an average of six to 12 months.” Pinterest Share on Twittercenter_img Share Share on Facebook Zhao said that over the last decade, more than 100 human trials aimed at Alzheimer’s disease treatment have been conducted with little success.Now, she’s part of a KU team that has published a breakthrough investigation into human ApoE2, a seemingly protective “apolipoprotein” created by the ApoE gene — a gene associated with Alzheimer’s disease risk. The research appears in the Journal of Alzheimer’s Disease 48(2).“Human ApoE is polymorphic and exists in three major alleles — ApoE2, ApoE3 and ApoE4,” Zhao said. “ApoE2 is a rare form and is considered neuroprotective. ApoE3 is the most common form and considered to play a neutral role in AD. ApoE4 is the greatest genetic risk factor for late-onset sporadic AD — ApoE4 occurs in only about 20 percent of the total population but accounts for approximately 50 percent of the Alzheimer’s disease population.”According to Zhao, too much previous research has focused on ApoE4 — many of them focused on ApoE4-mediated neurotoxic mechanisms by comparing ApoE4 to ApoE3, or ApoE4 carriers versus non-ApoE4 carriers. By contrast, she said ApoE2 has largely been ignored with only a few published studies that included ApoE2 in their designs — until now.“We took a different approach and looked from a different angle,” Zhao said. “We asked the question: What makes ApoE2 carriers resistant to Alzheimer’s disease? Our rationale is that if we can figure out the mechanisms that underlie ApoE2-mediated neuroprotective properties, we could translate this molecular understanding into a therapeutic strategy aimed to transform an aging brain — in particular an ApoE4 brain into an ApoE2-like brain. Such a strategy could essentially increase the defense ability of the aging, ApoE4 brain against the development of Alzheimer’s disease.”The KU researcher believes several factors could have contributed to the current trend of lost-in-translation from preclinical findings in animal models to trials in humans.“This could suggest that Alzheimer’s disease animal models that are widely used in preclinical studies — most are early-onset familial Alzheimer’s-disease-related models — don’t accurately model the pathophysiological condition of the majority of human Alzheimer’s disease cases, which is the late-onset sporadic Alzheimer’s disease — the most common form of Alzheimer’s disease representing over 95 percent of the current human Alzheimer’s disease population.”Thus, Zhao thinks it’s very likely the success derived from familial Alzheimer’s disease-related animal models isn’t replicated in human late-onset sporadic Alzheimer’s disease patients.“Another possibility could be that when the disease gets to the mid-to-late stage, the damage in the brain could be too advanced to be altered by the drugs tested in those trials,” she said.Zhao believes the trend of clinical failures stresses a tremendous need for the development of strategies that can be used for prevention, risk reduction or early intervention at the preclinical stage of the disease, in addition to continuing the effort of finding an effective treatment.“Alzheimer’s disease is a unique brain disease in that it begins with a very long preclinical development phase — 10 to 20 years — before it can be clinically diagnosed,” she said. “During this long prodromal period, the brain undergoes many changes including two major ones — decreased glucose utilization and increased amyloid deposition.”Zhao’s KU colleagues on the study published in the Journal of Alzheimer’s Disease are Jeriel Thomas-Richard Keeney and Shaher Ibrahimi.“This study essentially opens up a new line of research for us,” Zhao said. “We’re currently expanding our investigations to further test our hypothesis that bioenergetic robustness could serve as a major mechanism whereby ApoE2 delegates neuroprotection. If our hypothesis proves true, we can move forward with the idea that a strategy that enhances brain energy metabolism holds great promise for prevention, risk reduction or delaying the onset in an aging brain — in particular an ApoE4 brain — of Alzheimer’s disease.”last_img read more

first_imgShare on Facebook Pinterest Share Libidos of the young and spry can fire up at any point in the day, their energy levels spike during those post-lunch hours so those in their twenties should set their sex alarms for 3 p.m. The reason: In young adults, Kelley told the Telegraph, a neurotransmitter involved in inducing alertness, orexin, doesn’t overpower melatonin, the hormone at the helm of sleep-schedule regulation, until mid-morning. So, regardless of when the post-college set wakes up, they may not truly “wake up” until they’ve been out of bed for a bit.Couples in their thirties, however, should get it on at 8:20 a.m. As Kelley explains, sunlight revvs up testosterone in both men and women by stimulating the hypothalamus.For (early) middle-agers, it’s best for the mood to strike before turning in, around 10:20 p.m. Sex sparks the release of oxytocin, the “love” hormone, which can promote rest. Forty-somethings, according to Kelley, should aim to hit the sack before midnight, and rise at 7:50, when they’ll feel more naturally alert than younger adults.Fifty-somethings only need to tweak their sexing schedule slightly, as Kelley recommends getting after it even closer to bedtime. Sex: 10 p.m. → Sleep: 10:30 p.m. Also, these true middle-agers should indulge in any alcohol early in the evening, to give slowed-down livers time to break down the libido lubricants.Golden-agers should sync up with the air time of NCIS, and shoot for sex-having around 8 p.m. Older people naturally adopt an early-to-bed, early-to-rise schedule, and should try to fit in sex without disrupting their biological rewind.As for the amount? Well that, as always, remains up for debate.This article originally published by Van Winkle’s, vanwinkles.com, the editorial division of Casper Sleep LinkedIncenter_img Email There’s that great bit in Annie Hall when Annie and Alvy Singer are shown in splitscreen at their respective therapists’ offices. In response to their shrinks asking how often they have sex, Annie says, “Constantly. I’d say three times a week,” while Alvy laments: “Hardly ever, like three times a week.” It’s a funny scene for a few reasons, but most of all because it skewers the argument over the frequency with which people should engage in carnal delight. But perhaps there’s a metric to consider other than frequency: timing.The Telegraph enlisted Paul Kelley, a clinical research associate at Oxford University’s Sleep and Circadian Neuroscience Institute, to explain how couples in different age groups should set their coitus clocks.Why would age matter for scheduling sex? Because, as our circadian rhythms shift over the years, so too do the times of day when we’re most alert, sedate and primed for passion. Share on Twitterlast_img read more

first_imgShare Eighty percent of CS cases are caused by mutations in a gene called ERCC6, with codes for a protein called Cockayne Syndrome B (CSB). Past efforts to model the neurological aspects of the disease have proved difficult because existing mouse models do not display classical neurological symptoms.“What we have needed is a robust human in vitro cellular model – a so-called ‘disease in a dish’ – that would allow us to understand fundamentally what is happening and which could point us toward possible therapeutic targets and treatments,” said senior author Alysson R. Muotri, PhD, associate professor in the UC San Diego School of Medicine departments of Pediatrics and Cellular and Molecular Medicine.Muotri and colleagues have previously used induced pluripotent stem cells to create neuronal models of autism spectrum disorders. Mirroring those earlier efforts, Muotri and his team generated the in vitro CS cell model by taking skin cells from two individuals with CS, reverting them to induced pluripotent stem cells, then reprogramming the stem cells to differentiate as neural progenitor cells and neurons. The neurons subsequently formed functioning networks, popularly dubbed “mini-brains.”The CS networks allowed researchers to identify areas of cellular dysfunction compared to normal neuronal networks from control models. Specifically, they noted that CSB-deficient neuronal networks displayed altered electrophysiological activity, including diminished ability to grow synaptic connections to other neurons and synchronize activities.“This work provides an alternative to existing models for studying neural-specific aspects of CS,” said Muotri. “It reveals that CSB protein is required for normal neuronal function. It shows the feasibility of constructing a new and relevant human in vitro model with potential clinical interest.” LinkedIn Share on Facebook Pinterestcenter_img Email Researchers at University of California, San Diego School of Medicine and Rady Children’s Hospital-San Diego have created the first stem cell-derived in vitro cellular model of a rare, but devastating, neurodegenerative condition called Cockayne syndrome (CS).The findings are published in the current online issue of the journal Human Molecular Genetics.CS is characterized by short stature and an appearance of premature aging. Traits include extreme sensitivity to sunlight, abnormally small head size (microcephaly), impaired development of the nervous system, eye problems and a failure to gain weight and grow at the expected rate, called “failure to thrive.” While specific symptoms of CS may be treatable, there is no cure and prognosis is poor. Most patients do not survive past their twenties. Share on Twitterlast_img read more

first_imgShare on Twitter The research indicates that people living in self-oriented cultures — such as Canada, the United States, Australia or Great Britain — were less emotionally complex than people living in other-oriented cultures with a greater emphasis on feelings of duty and familial bonds. People in various parts of Asia and Russia showed considerably more complexity in their emotions. Western Europe and South Africa fell in the middle.“People in those other-oriented cultures are more likely to experience emotional complexity because they are able to see different perspectives,” said Grossmann. “For example, they might see a job loss as disappointing, but also as an exciting opportunity to spend more time with family or to try something new. Someone from a culture that is oriented towards personal achievement is more likely to see it as all negative.”This project involved three studies. One of them used a text-analysis tool to measure the prevalence of mixed emotional expressions in 1.3 million English-language websites and blogs. The other two studies focused on the ways in which people report their emotions across a range of daily experiences, examining whether they report experiencing mixed feelings, and whether they differentiate between different types of positive and negative experiences.“Across the entire project, the degree to which a culture promotes focus on other people rather than the self, including greater awareness of others, was positively associated with all of the markers of emotional complexity,” said Grossmann. “Further, when we looked at individuals who focus on others within each culture, they also showed greater emotional complexity on a personal level.”The paper appears in the most recent issue of the Journal of Personality and Social Psychology. Share on Facebook Email Experiencing mixed emotions shows emotional complexity, not indecision, and people living in different parts of the world vary in their ability to distinguish between multiple feelings they’re having at once, according to new research.A project from the University of Waterloo examined how people across 16 cultures vary in their tendency to see situations as either all good or all bad, or in a more complex fashion by seeing a little of both. Previous studies have linked lower emotional complexity with a reduced ability to control one’s emotions, and higher incidence of depression.“People in many western countries see mixed feelings as undesirable — as if to suggest that someone experiencing mixed feelings is wishy-washy,” said Igor Grossmann, a professor in the Department of Psychology at Waterloo, and lead author of the paper. “Actually, we found that both westerners and non-westerners who show mixed feelings are better able to differentiate their emotions and experience their lives in an emotionally rich and balanced fashion.”center_img Pinterest Share LinkedInlast_img read more

first_imgShare on Twitter Pinterest LinkedIn With this groundwork laid, the researchers formulated a straightforward hypothesis. “If GLP-1 regulates intake of palatable food, then perhaps it also regulates consumption of cocaine,” Schmidt said. “That was it in a nutshell.”The hypothesis turned out to be true. In a two-and-a-half year study of rats, the trio showed that when they activated GLP-1 receptors in the region of the brain that deals with reward behavior, called the ventral tegmental area, or VTA, the animals self-administered less cocaine. It’s the first time such a role has been shown for GLP-1 in the brain.Physiologically, GLP-1 acts similarly in rat brains and human brains. Rather than injecting cocaine, the scientists modeled the way a human would take the drug by offering the study rats a lever to press for intravenous infusions. Once the animals stabilized in their drug-taking regimen, the researchers introduced the GLP-1 receptor agonist directly into the brain.“We’re looking at what activation of GLP-1 receptors in the VTA does to the animal’s self-administration of cocaine,” Schmidt said. “We were able to show a nice decrease in cocaine self-administration.”Though no human trials have been completed, something Schmidt acknowledges is still several steps away, there’s one fewer barrier because of the drug’s FDA approval. Clinicians have likely already heard of it, and those with a particular patient population have potentially already prescribed it. The drug, whose side effects are known, has already been proven safe for human use.Getting to human clinical trials would go a long way toward meeting a long-term goal for Schmidt, who is lead author on a new paper detailing these findings in the Nature journal Neuropsychopharmacology. “Our interest is really to understand how chronic exposure to drugs of abuse changes the brain to produce addiction-like behaviors,” said Schmidt, who has also authored another similiar paper, about nicotine and a potential smoking-cessation medication.To move forward the GLP-1 project specifically, Schmidt said the team plans to next focus on the pathway it follows in the brain.“That gets into a systems neuroscience approach, into the circuitry underlying the behavior,” he said. “It’s really provocative…. We talk about the VTA and the reward circuit that drives cocaine taking. But there’s also this pathway that cocaine is activating that’s functioning as a ‘brake’ to try and stop or reduce the behavior.”There are more pieces of the puzzle to solve. But, if this research continues to progress successfully, those working to treat cocaine addiction may soon have another option in their toolkit. Sharecenter_img In the ongoing fight against drug addiction, researchers from the University of Pennsylvania’s School of Nursing and Perelman School of Medicine have discovered a unique application for an FDA-approved drug currently used for obese patients and type 2 diabetics: treatment for cocaine dependence.The drug, trade name Byetta, derives from a naturally occurring hormone called glucagon-like peptide-1, or GLP-1, which regulates feeding behavior. Knowing what they did about GLP-1, Matthew Hayes and Heath Schmidt, of Nursing and of Psychiatry, and Bart De Jonghe, of Nursing, turned to it as a possible treatment for cocaine addicts.Previously, Hayes, whose primary appointment is at the Perelman School of Medicine, had completed a GLP-1 study comparing consumption of palatable food to normal chow: as Schmidt put it, a burger and fries versus a salad. Activation of GLP-1 receptors in a specific part of the brain, according to this work, reduced intake of that burger meal but did nothing, good or bad, to salad consumption. Additionally, previous literature showed an overlap between the neural circuits that influence feeding and drug taking. Email Share on Facebooklast_img read more